CD2 Monoclonal Antibody,FITC Conjugated

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P06729

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Background

This antibody recognizes a 50KDa lymphocyte surface antigen which is expressed on all peripheral blood T lymphocytes,the majority of lymphocytes and malignant cells of T cell origin, including T ALL cells. Normal B lymphocytes, monocytes or granulocytes do not express surface CD2 antigen, neither do common ALL cells. CD2 antigen has been characterised as the receptor for sheep erythrocytes. This CD2 monoclonal antibody inhibits E rosette formation. CD2 antigen also functions as the receptor for the CD58 antigen(LFA-3). 1. Ledbetter, J et al.  (1981) J Exp Med  153:310-323.2. Haynes , B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD2

Research Areas

Immunology;Stem cells