CD1D Polyclonal Antibody

Ab type

Primary antibody

Background

CD1D encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Antigen-presenting glycoprotein CD1d at AA range: 161-210

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

37717

synonyms

CD1D; Antigen-presenting glycoprotein CD1d; R3G1; CD1d