CD19 Monoclonal Antibody,APC Conjugated

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P15391

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Background

COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate.* CD19 is a key phenotyping marker of non-T cell leukemia.1.  Nadler, LM et al. (1983) J. Immunol. 131:2442. Schlossman, SL et al., eds. (1995)  Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York.3.  Tedder T. et al.  (1994)  Immunol Today. 15:437-442

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD19

Research Areas

Immunology;Stem cells