CD141 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

60329

synonyms

THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141