CD138 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein (syndecan 1) encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of SDC1 and encode the same protein.

Reactivity

Human;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SDC1. AA range:91-140

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

32462

synonyms

SDC1; SDC; Syndecan-1; SYND1; CD antigen CD138