CD133 Polyclonal Antibody

Ab type

Primary antibody

Background

PROM1 encodes a pentaspan transmembrane glycoprotein. Prominin-1 localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human PROM1. AA range:41-90

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

97202

synonyms

PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133