CCM2 Antibody

Size

100ul

Clone Number

Aliases

C7orf22 antibody; Ccm2 antibody; CCM2 gene antibody; CCM2_HUMAN antibody; Cerebral cavernous malformation 2 antibody; Cerebral cavernous malformations 2 protein antibody; Chromosome 7 open reading frame 22 antibody; Malcavernin antibody; MGC4067 antibody; MGC4607 antibody; MGC74868 antibody; OSM antibody; Osmosensing scaffold for MEKK3 antibody; OTTHUMP00000159554 antibody; OTTHUMP00000214270 antibody; OTTHUMP00000214271 antibody; OTTHUMP00000214273 antibody; PP10187 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BSQ5

Immunogen

Recombinant Human Cerebral cavernous malformations 2 protein (1-300AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CCM2

Research Areas

Neuroscience; Signal transduction