CCDB1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene was identified by the interaction of its gene product with Grap2| a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase| and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CCDB1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

39600

synonyms

CCDB1