CCD50 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a soluble| cytoplasmic| tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic| postlingual| progressive sensorineural DFNA44 hearing loss. In mouse| the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CCD50

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

33660

synonyms

CCD50