CCAR1 Antibody

Size

100ul

Clone Number

Aliases

CARP-1 antibody; Carp1 antibody; Ccar1 antibody; CCAR1_HUMAN antibody; Cell cycle and apoptosis regulatory protein 1 antibody; cell division cycle and apoptosis regulator 1 antibody; Cell division cycle and apoptosis regulator protein 1 antibody; Death inducer with SAP domain antibody; FLJ10590 antibody; FLJ10839 antibody; FLJ13376 antibody; FLJ20734 antibody; MGC7730 antibody; RP11-437A18.1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8IX12

Immunogen

Recombinant Human Cell division cycle and apoptosis regulator protein 1 protein (1-200AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CCAR1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism