ABCbiolab
SKU:ABCB11683
CC14B Polyclonal Antibody
CC14B Polyclonal Antibody
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Ab type
Primary antibody
Background
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Reactivity
Human, Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from part region of human protein
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
synonyms
Dual specificity protein phosphatase CDC14B ;EC 3.1.3.16;EC 3.1.3.48;CDC14 cell division cycle 14 homolog B
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