CBY1 Antibody

Size

100ul

Clone Number

Aliases

ARPP-binding protein antibody; C22orf2 antibody; CBY antibody; Cby1 antibody; CBY1_HUMAN antibody; Cytosolic leucine rich protein antibody; Cytosolic leucine-rich protein antibody; Golgi and endoplasmic reticulum-associated 1 antibody; HRIHFB2025 antibody; PIGEA 14 antibody; PIGEA-14 antibody; PKD2 interactor antibody; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 antibody; Protein Chibby antibody; Protein chibby homolog 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y3M2

Immunogen

Recombinant Human Protein chibby homolog 1 protein (1-126AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CBY1

Research Areas

Epigenetics and Nuclear Signaling; Signal transduction; Stem cells