CBX4 Antibody

Size

100ug

Clone Number

Aliases

CBX 4 antibody; CBX4 antibody; Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody; CBX4_HUMAN antibody; Chromobox homolog 4 (Pc class homolog; Drosophila) antibody; Chromobox homolog 4 antibody; Chromobox protein homolog 4 antibody; E3 SUMO protein ligase CBX 4 antibody; E3 SUMO protein ligase CBX4 antibody; E3 SUMO-protein ligase CBX4 antibody; hPc 2 antibody; hPc2 antibody; NBP 16 antibody; NBP16 antibody; NS5ATP1 binding protein 16 antibody; Pc 2 antibody; Pc class 2 homolog antibody; Pc class homolog antibody; Pc class homolog Drosophila antibody; PC2 antibody; Polycomb 2 homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00257

Immunogen

Recombinant Human E3 SUMO-protein ligase CBX4 protein (1-160AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CBX4

Research Areas

Epigenetics and Nuclear Signaling