CBX2 Polyclonal Antibody

Ab type

Primary antibody

Background

CBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male-to-female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for CBX2.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human CBX2.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

56081

synonyms

CBX2; Chromobox protein homolog 2