CAVIN1 Antibody, HRP conjugated

Size

100ul

Clone Number

Aliases

2310075E07Rik antibody; AW546441 antibody; Cavin 1 antibody; Cavin antibody; Cavin-1 antibody; CAVIN1 antibody; CGL4 antibody; FKSG13 antibody; FLJ90031 antibody; MGC118550 antibody; OTTMUSP00000002049 antibody; Polymerase I and transcript release factor antibody; Ptrf antibody; PTRF_HUMAN antibody; RNA polymerase I and transcript release factor antibody; RP23-279L23.6 antibody; TTF I interacting peptide 12 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6NZI2

Immunogen

Recombinant Human Caveolae-associated protein 1 protein (12-44AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues (PubMed:18056712, PubMed:18191225, PubMed:19726876). Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CAVIN1

Research Areas

Epigenetics and Nuclear Signaling