Cathepsin H Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by CTSH is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein (cathepsin H), which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of CTSH has been correlated with malignant progression of prostate tumors. Alternate splicing of CTSH results in multiple transcript variants encoding different isoforms.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Cathepsin H . at AA range: 70-150

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

37378

synonyms

CTSH; CPSB; Pro-cathepsin H