CATB Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase| shows peptidyl-dipeptidase activity| liberating C-terminal dipeptides.|Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.|Belongs to the peptidase C1 family.|subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.|subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.|

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CATB (Cleaved-Leu80)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

37290

synonyms

CATB ;Cleaved-Leu80; Cathepsin B; EC 3.4.22.1; APP secretase; APPS; Cathepsin B1; Cathepsin B light chain; Cathepsin B heavy chain;