CARMIL2 Antibody

Size

100ul

Clone Number

Aliases

CARMIL2 antibody; CARMIL2b antibody; Leucine rich repeat containing 16C antibody; leucine-rich repeat antibody; Leucine-rich repeat-containing protein 16C antibody; LR16C_HUMAN antibody; LRRC16C antibody; RGD antibody; RGD leucine rich repeat tropomodulin and proline rich containing protein antibody; RGD motif leucine rich repeats tropomodulin domain and proline rich containing antibody; Rltpr antibody; tropomodulin and proline-rich-containing protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6F5E8

Immunogen

Recombinant Human Capping protein, Arp2/3 and myosin-I linker protein 2 protein (1136-1290AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IP; Recommended dilution: WB:1:500-1:2000, IP:1:200-1:2000

Background

Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization (PubMed:26466680). Plays a role in cell protrusion formations; involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations (PubMed:19846667, PubMed:26578515, PubMed:26466680). Involved as well in cell migration and invadopodia formation during wound healing (PubMed:19846667, PubMed:26578515, PubMed:26466680).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CARMIL2

Research Areas

Cell biology