CAMKK2 Antibody

Size

100ug

Clone Number

Aliases

Calcium/calmodulin dependent protein kinase beta antibody; Calcium/calmodulin dependent protein kinase kinase 2 antibody; Calcium/calmodulin dependent protein kinase kinase 2 beta antibody; Calcium/calmodulin dependent protein kinase kinase beta antibody; Calcium/calmodulin-dependent protein kinase kinase 2 antibody; Calcium/calmodulin-dependent protein kinase kinase beta antibody; CaM kinase kinase beta antibody; CaM KK beta antibody; CaM-kinase kinase 2 antibody; CaM-kinase kinase beta antibody; CaM-KK 2 antibody; CaM-KK beta antibody; CaMKK 2 antibody; CAMKK antibody; CaMKK beta antibody; CAMKK beta protein antibody; Camkk2 antibody; CAMKKB antibody; KKCC2_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96RR4

Immunogen

Recombinant Human Calcium/calmodulin-dependent protein kinase kinase 2 protein (5-148AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CAMKK2

Research Areas

Cancer; Signal transduction