CACNA1B Antibody

Size

100ul

Clone Number

Aliases

CACNA1B antibody; CACH5 antibody; CACNL1A5 antibody; Voltage-dependent N-type calcium channel subunit alpha-1B antibody; Brain calcium channel III antibody; BIII antibody; Calcium channel antibody; L type antibody; alpha-1 polypeptide isoform 5 antibody; Voltage-gated calcium channel subunit alpha Cav2.2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q00975

Immunogen

Recombinant Human Voltage-dependent N-type calcium channel subunit alpha-1B protein (2132-2339AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the \'high-voltage activated\' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CACNA1B

Research Areas

Signal transduction