CABIN1 Antibody

Size

100ug

Clone Number

Aliases

A330070M20Rik antibody; Cabin 1 antibody; CABIN_HUMAN antibody; Cabin1 antibody; CAIN antibody; Calcineurin binding protein cabin 1 antibody; Calcineurin inhibitor antibody; Calcineurin-binding protein cabin-1 antibody; KIAA0330 antibody; PPP3IN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y6J0

Immunogen

Recombinant Human Calcineurin-binding protein cabin-1 protein (1978-2123AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background

May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it\\\'s target genes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CABIN1

Research Areas

Signal transduction