CA XIII Polyclonal Antibody

Ab type

Primary antibody

Background

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XIII, also referred to as carbonate dehydratase XIII, is predominantly expressed in spleen, prostate, thymus, ovary, testis, colon and small intestine localizing to the cytoplasm. It exhibits highest homology with family members CA I, CA II and CA III. CA XIII may play a role in embryogenesis. Efficient inhibitors of CA XIII activity are sulfanilyl-sulfonamide type inhibitors.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CA13. AA range:141-190

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

29443

synonyms

CA13; Carbonic anhydrase 13; Carbonate dehydratase XIII; Carbonic anhydrase XIII; CA-XIII