C4BPB Antibody

Size

100ul

Clone Number

Aliases

C4b binding protein beta chain antibody; C4b-binding protein beta chain antibody; C4BP antibody; C4BPB antibody; C4BPB_HUMAN antibody; Complement component 4 binding protein beta antibody; Complement component 4 binding protein beta chain antibody; Complement component 4-binding protein beta antibody; OTTHUMP00000034288 antibody; OTTHUMP00000034289 antibody; OTTHUMP00000034375 antibody; OTTHUMP0000003474 antibody; Proline rich protein antibody; PRP antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P20851

Immunogen

Recombinant Human C4b-binding protein beta chain protein (18-252AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

C4BPB

Research Areas

Immunology