C2CD3 Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

C2CD3 antibody; C2 domain-containing protein 3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q4AC94

Immunogen

Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

C2CD3

Research Areas

Others