C1q-C Polyclonal Antibody

Ab type

Primary antibody

Background

C1QC (complement C1q C chain) encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QC encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for C1QC.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human C1QC. AA range:81-130

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

25774

synonyms

C1QC; C1QG; Complement C1q subcomponent subunit C