C1INH Polyclonal Antibody

Ab type

Primary antibody

Background

SERPING1encodes a highly glycosylated plasma protein (serpin family G member 1)involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SERPING1. AA range:342-391

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

55154

synonyms

SERPING1; C1IN; C1NH; Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1