c-Src(Phospho Tyr419) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr418. AA range:386-435

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

59704

synonyms

Proto-oncogene tyrosine-protein kinase Src; SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src