c-Rel(Phospho Ser503) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold| plexin| transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis| inflammation| the immune response| and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas| including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Rel around the phosphorylation site of Ser503. AA range:470-519

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

68520

synonyms

Proto-oncogene c-Rel; REL; Proto-oncogene c-Rel