c-Myb Polyclonal Antibody

Ab type

Primary antibody

Background

MYB encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. MYB may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MYB. AA range:496-545

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

72341

synonyms

MYB; Transcriptional activator Myb; Proto-oncogene c-Myb