c-Fos(Phospho Ser374) Polyclonal Antibody

Ab type

Primary antibody

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Fos around the phosphorylation site of Ser374. AA range:331-380

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

40695

synonyms

Proto-oncogene c-Fos; FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7