BSND Antibody

Size

100ul

Clone Number

Aliases

BART antibody; Bartter syndrome infantile with sensorineural deafness antibody; Bartter syndrome; infantile; with sensorineural deafness (Barttin) antibody; Barttin antibody; Bsnd antibody; BSND_HUMAN antibody; deafness; autosomal recessive 73 antibody; DFNB 73 antibody; DFNB73 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WZ55

Immunogen

Recombinant Human Barttin protein (54-320AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BSND

Research Areas

Neuroscience; Metabolism; Signal transduction