BRMS-1 Polyclonal Antibody

Ab type

Primary antibody

Background

BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

28461

synonyms

BRMS1; Breast cancer metastasis-suppressor 1