BRAT1 Antibody

Size

100ul

Clone Number

Aliases

BAAT 1 antibody; BAAT1 antibody; BRAT 1 antibody; brat1 antibody; BRAT1_HUMAN antibody; BRCA1-associated ATM activator 1 antibody; BRCA1-associated protein required for ATM activation protein 1 antibody; BRCA1-associated protein required for ATM activation-1 antibody; C7orf27 antibody; chromosome 7 open reading frame 27 antibody; HEAT repeat containing protein C7orf27 antibody; MGC22916 antibody; RMFSL antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6PJG6

Immunogen

Recombinant Human BRCA1-associated ATM activator 1 protein (603-821AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500

Background

Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BRAT1

Research Areas

Epigenetics and Nuclear Signaling