Bradykinin B1 R Polyclonal Antibody

Ab type

Primary antibody

Background

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for BDKRB1.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

40495

synonyms

BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor