botF Antibody

Size

100ul

Clone Number

Aliases

botFBotulinum neurotoxin type F antibody; BoNT/F antibody; Bontoxilysin-F) [Cleaved into: Botulinum neurotoxin F light chain antibody; LC antibody; EC 3.4.24.69); Botulinum neurotoxin F heavy chain antibody; HC)] antibody

Immunogen Species

Clostridium botulinum

UniProt ID

P30996

Immunogen

Recombinant Clostridium botulinum Botulinum neurotoxin type F protein (1-436AA)

Raised in

Rabbit

Species Reactivity

Clostridium botulinum

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the \'58-Gln-|-Lys-59\' bond of synaptobrevins-1 and -2.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

botF

Research Areas

N/A