BMPR1B Antibody

Size

100ug

Clone Number

Aliases

Activin receptor like kinase 6 antibody; Acvrlk6 antibody; ALK 6 antibody; ALK6 antibody; alk6tr antibody; BMP type-1B receptor antibody; BMPR IB antibody; BMPR-1B antibody; Bmpr1b antibody; BMPRIB antibody; BMR1B_HUMAN antibody; Bone morphogenetic protein receptor type 1B antibody; Bone morphogenetic protein receptor type IB antibody; Bone morphogenetic protein receptor type-1B antibody; BR 1b antibody; BR1b antibody; CDw 293 antibody; CDw293 antibody; CDw293 antigen antibody; CFK 43a antibody; CFK43a antibody; Serine/threonine receptor kinase antibody; zALK 6 antibody; zALK6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00238

Immunogen

Recombinant Human Bone morphogenetic protein receptor type-1B protein (14-126AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BMPR1B

Research Areas

Epigenetics and Nuclear Signaling; Signal transduction; Stem cells