BMP-10 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human BMP-10.

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

48047

synonyms

Bone morphogenetic protein 10; BMP10; Bone morphogenetic protein 10; BMP-10