BMAL2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER| ARNT| SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels| exposure to certain environmental pollutants| and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein| the structurally related MOP4| and hypoxia-inducible factors| such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors| this protein is coexpressed in regions of the brain such as the thalamus| hypothalamus| and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human BMAL2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

69960

synonyms

BMAL2