BHLHA15 Antibody

Size

100ug

Clone Number

Aliases

Basic helix loop helix domain containing class B 8 antibody; Basic helix loop helix family member a15 antibody; BHA15_HUMAN antibody; Bhlha15 antibody; bHLHB8 antibody; Class A basic helix-loop-helix protein 15 antibody; Class B basic helix-loop-helix protein 8 antibody; Class II bHLH protein MIST1 antibody; intestine and stomach expression 1 antibody; MIST 1 antibody; MIST-1 antibody; MIST1 antibody; Muscle antibody; Muscle intestine and stomach expression 1 antibody; protein MIST1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7RTS1

Immunogen

Recombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5\'-CANNTG-3\' (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BHLHA15

Research Areas

Epigenetics and Nuclear Signaling