BEX2 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

BEX2Protein BEX2 antibody; Brain-expressed X-linked protein 2 antibody; hBex2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BXY8

Immunogen

Recombinant Human Protein BEX2 protein (1-128AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BEX2

Research Areas

Others