BART1 Polyclonal Antibody

Ab type

Primary antibody

Background

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ARL2BP. AA range:101-150

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

18822

synonyms

ARL2BP; BART; BART1; ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; Binder of ARF2 protein 1