BANP Antibody

Size

100ul

Clone Number

Aliases

AAH09424 antibody; Banp antibody; BANP_HUMAN antibody; BEN domain-containing protein 1 antibody; BEND1 antibody; BTG3 associated nuclear protein isoform a antibody; Btg3-associated nuclear protein antibody; DKFZp761H172 antibody; FLJ 10177 antibody; FLJ 20538 antibody; FLJ10177 antibody; FLJ20538 antibody; Protein BANP antibody; Scaffold/Matrix associated region 1 antibody; Scaffold/matrix-associated region-1-binding protein antibody; SMAR 1 antibody; SMAR1 antibody; SMARBP 1 antibody; SMARBP1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N9N5

Immunogen

Recombinant Human Protein BANP protein (1-260AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 \\\'Ser-15\\\' phosphorylation and nuclear accumulation, which causes cell cycle arrest.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BANP

Research Areas

Epigenetics and Nuclear Signaling