BANF1 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

BAF antibody; BAF_HUMAN antibody; BANF 1 antibody; BANF1 antibody; Barrier to autointegration factor 1 antibody; Barrier to autointegration factor antibody; Barrier-to-autointegration factor antibody; BCRG 1 antibody; BCRG1 antibody; BCRP 1 antibody; BCRP1 antibody; Breakpoint cluster region protein 1 antibody; D14S1460 antibody; MGC111161 antibody; NGPS antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75531

Immunogen

Recombinant Human Barrier-to-autointegration factor protein (2-89AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BANF1

Research Areas

Microbiology