BACE2 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 210-290

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Beta-secretase 2 ;EC 3.4.23.45;Aspartic-like protease 56 kDa;Aspartyl protease 1;ASP1;Asp 1;Beta-site amyloid precursor protein cleaving enzyme 2;Beta-site APP cleaving enzyme 2;Down reg