BACE2 Antibody

Size

100ug

Clone Number

Aliases

ALP 56 antibody; ALP56 antibody; Asp 1 antibody; ASP1 antibody; ASP21 antibody; Aspartic Like Protease 56kDa antibody; Aspartic-like protease 56 kDa antibody; Aspartyl protease 1 antibody; BACE 2 antibody; Bace2 antibody; BACE2_HUMAN antibody; Beta Secretase 2 antibody; Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2 antibody; Beta-secretase 2 antibody; Beta-site amyloid precursor protein cleaving enzyme 2 antibody; Beta-site APP cleaving enzyme 2 antibody; Down region aspartic protease antibody; Downs Syndrome Region Aspartic Protease antibody; DRAP antibody; Memapsin 1 antibody; Memapsin-1 antibody; Membrane associated aspartic protease 1 antibody; Membrane-associated aspartic protease 1 antibody; Theta-secretase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5Z0

Immunogen

Recombinant Human Beta-secretase 2 protein (84-157AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BACE2

Research Areas

Neuroscience; Cell biology