BACE1 Antibody

Size

100ul

Clone Number

7G3

Aliases

Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2), BACE1, BACE KIAA1149

Immunogen Species

Homo sapiens (Human)

UniProt ID

P56817

Immunogen

A synthesized peptide derived from human BACE1

Raised in

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

BACE1

Research Areas

Neuroscience; Cell biology