BACE (Acetyl Lys316) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques| which accumulate in the brains of human Alzheimer's disease patients.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human BACE (Acetyl Lys316)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

55110

synonyms

BACE ;Acetyl Lys316; Beta-secretase 1; EC 3.4.23.46; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2