AZI2 Antibody

Size

100ug

Clone Number

Aliases

5 azacytidine induced protein 2 antibody; 5-azacytidine-induced protein 2 antibody; AA410145 antibody; AZ2 antibody; AZI2 antibody; AZI2_HUMAN antibody; MGC112644 antibody; Nak associated protein 1 antibody; Nak-associated protein 1 antibody; NAP1 antibody; NF kappa B activating kinase associated protein 1 antibody; NF-kappa-B-activating kinase-associated protein 1 antibody; TILP antibody; TILP(S) antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H6S1

Immunogen

Recombinant Human 5-azacytidine-induced protein 2 protein (258-376AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

AZI2

Research Areas

Epigenetics and Nuclear Signaling; Signal transduction