ATPIF1 Antibody

Size

100ul

Clone Number

Aliases

ATIF1_HUMAN antibody; ATP synthase inhibitor protein antibody; ATPase inhibitor antibody; ATPase inhibitor mitochondrial antibody; ATPase inhibitor protein antibody; ATPase inhibitory factor 1 antibody; ATPI antibody; ATPIF 1 antibody; Atpif1 antibody; ATPIP antibody; IF(1) antibody; IF1 antibody; Inhibitor of F(1)F(o)-ATPase antibody; IP antibody; MGC1167 antibody; MGC8898 antibody; mitochondrial antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UII2

Immunogen

Recombinant Human ATPase inhibitor, mitochondrial protein (26-106AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Endogenous F1F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F1F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F1F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ATPIF1

Research Areas

Cancer; Tags & Cell Markers; Metabolism; Signal transduction