ATP5F1C Antibody

Size

100ug

Clone Number

Aliases

ATP synthase gamma chain; mitochondrial antibody; ATP synthase subunit gamma antibody; ATP synthase subunit gamma; mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F1 complex; gamma polypeptide 1 antibody; ATP synthase; H+ transporting; mitochondrial F1 complex; gamma subunit antibody; ATP5C 1 antibody; ATP5C antibody; ATP5C1 antibody; ATP5CL1 antibody; ATPG_HUMAN antibody; F ATPase gamma subunit antibody; F-ATPase gamma subunit antibody; mitochondrial antibody; Mitochondrial ATP synthase; gamma subunit 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P36542

Immunogen

Recombinant Human ATP synthase subunit gamma, mitochondrial protein (156-266AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ATP5C1

Research Areas

Tags & Cell Markers; Metabolism; Signal transduction